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Size Exclusion Resins
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Instruments and Reagent
Exoplorer Nano-flow Cytometer
Polyethylenimine (PEI) Transfection Reagent
Magnetic Rack
Exoplorer Nano-flow Cytometer
sample


The ExoplorerTM Nano-flow Cytometer is a cutting-edge instrument designed primarily for the characterization of biological nanoparticles, including exosomes, viruses, LNPs, bacteria, subcellular subunits, and other nanoparticles. Offering exceptional sensitivity, resolution, and throughput, the ExoplorerTM Nano-flow Cytometer facilitates a comprehensive analysis of nanoparticles within the 5-3000 nm range. This capability extends to size distribution, particle counting, and biochemical property assessment, making it a groundbreaking tool for life science and biomedical research.

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The ExoplorerTM Nano-flow Cytometer Instrument Specifications

The ExoplorerTM Nano-flow Cytometer Instrument   Specifications

Fluidics Station

Dimensions

386*342*425mm (L*D*H)

Weight (including containers, tubing, and cables)

9.5KG

Flow Cytometer

Dimensions

630*460*460mm (L*D*H)

Weight

49.5KG

Electrical Parameters

Power Supply Voltage

100-240V

Frequency

50/60Hz

Power

300VA

Sampling

Tube Specifications

5 ml   tube, 1.5 and 2.0 ml EP tubes

Maximum Single Loading Volume

50μl

Event Processing Speed

34,000 events/s


The ExoplorerTM Nano-flow Cytometer Data Management

The ExoplorerTM Nano-flow Cytometer Data Management

Operating   Software

Exoplorer Software

Language   Support

English, Chinese

FCS Version

FCS 3.1

Recommended

Computer

Configuration

Operating System

64-bit   Windows 10 Professional and Windows 11 Professional

Processor

Equivalent   to or better than 12th Gen Intel(R) Core (TM) i7-12700

Memory

32GB

Storage Space

1TB solid-state drive

Resolution

1080P (1920*1080)

USB

2 USB 3.0 ports / 3 USB 2.0 ports

Quality Control

Tracking and recording of quality control results, with exportable quality control reports

Compliance with 21CFR electronic signature requirements

Safety   Standards

IEC   61326-2-6:2020

EN   60825-1:2014+A11:2021

IEC   60825-1:2014

IEC   61010-2-081:2019

IEC   61010-1:2010/AMD1:2016

EN   61010-1:2010

EN   61010-1:2010/A1:2019

EN   61010-2-081:2020

EN IEC   61326-1:2021

EN IEC   61326-2-6:2021

EN IEC   61000-3-2:2019+A1:2021

EN   61000-3-3:2013/A2:2021 (Except: Risk Management Evaluation)


The ExoplorerTM Nano-flow Cytometer Features and Advantages

4 Scatter Channels

• 4 scatter channelsVSSC-1, VSSC-2, FSC, and BSSC.

• Detectable particle range: 5nm-3000nm.

• ExoplorerTM supports three signal parameters (area, height, and width), effectively distinguishing system background and noise, ensuring accurate optical signal capture.

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Dual Lasers/ 8 Fluorescence Channels

• Equipped with dual lasers (violet laser and blue laser) and up to 8 fluorescence channels.

• Accurate detection of every signal peak from 8-peak beads.

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Sizing Reference Function

A standard algorithm is used for curve fitting to calculate particle size. Sizing results are given in nm and refractive index of the /biological sample is used to determine the size.

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Bead-free Absolute Counting

Feature exceptional consistency, stability, and reliability in absolute counting functionality.

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Multiple Fluorescent Markers Supported

Empower multicolor schemes and elevate multicolor experiments.

Lipid Nanoparticles

Unstained

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Stained

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Extracellular Vesicles

Unstained

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Stained

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Plasma

Unstained

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Stained

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LNP Detection

LNP Carrying Nucleic Acid Positivity Rate

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LNP Sizing and Concentration Data


Sample

Dilution Factor

Detection Concentration

(Particles/mL)

Original Concentration

(Particles/mL)

RSD

Sizing:Median

LNP

160000

2.866E+08

4.585E+13

2%

63.3

640000

7.352E+07

4.705E+13

62.7

2560000

1.836E+07

4.700E+13

62.5


LNP samples at different dilution factors were acquired, with a calculated original concentratioon RSD of 2%.

Experimental results demonstrate the ExoplorerTM excels in measuring the concentration, particle size and shell rate of LNPs.


Supreme Robust System Stability

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User-Friendly Design

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The ExoplorerTM Nano-flow Cytometer Applications


Size Distribution

Count/Concentration

Detection

Fluorescence

Labeling

Other

Characterizations


Total   Size

Distribution

Size   Distribution

of   Any Subgroup

Size-Function

Correlated   Analysis



Empty   Shell Rate

Aggregates

Exosomes



Viruses

Lipid

Nanoparticles


Bacteria



Subcellular

Units



Other

Nanoparticles



Apply for a free sample: Request a Sample

Contact our team: vdo@vdobiotech.com






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