Ion exchange chromatography is one of the most widely used methods for protein separation and purification. Different proteins have different isoelectric points, different molecular sizes, different charge density distributions in the same mobile phase, different charge amounts, different binding strengths to ion exchange resin with opposite charges, and different retention times when eluting in the mobile phase, thus allowing separation.

Vdo Biotech provides a comprehensive portfolio of ion exchange media. Our product lines feature four key ligands—SP, Q, CM, and DEAE, precisely paired with a range of advanced matrices, including Focurose FF, Focurose HP, Focurose XL, and Focurose HPR. This sophisticated design ensures our media aligns with purification schemes in downstream bioprocessing, and offering tailored-

purification strategies to our customer.

Resin Selection Principles

★ Capture Stage

Select high-flow, high-DBC ion exchange media (e.g., XL-series matrices) for rapid processing and maximal binding capacity.

★ Intermediate Purification

Select media balancing high DBC and superior resolution (e.g., FF/XL matrices) for impurity clearance without yield compromise.

★ Polishing Stage

Select high-resolution, high-recovery media (e.g., HP/FF/HPR matrices) for final product quality control.

New Products——VDX Series IEX Resins

VDX Series Products represent Vdo Biotech's premium chromatography media line with fully independent intellectual property rights. They deliver high performance, superior selectivity, and cost-efficiency, addressing the market's urgent demand for high-performance bioprocessing consumables.VDX Series ion exchange media are categorized into three lines based on following performance characteristics:High-Resolution, High-Capacity, Strong-Binding.