The Exoplorer^TM Nano-flow Cytometer is a cutting-edge instrument designed primarily for the characterization of biological nanoparticles, including exosomes, viruses, LNPs, bacteria, subcellular subunits, and other nanoparticles. Offering exceptional sensitivity, resolution, and throughput, the Exoplorer^TM Nano-flow Cytometer facilitates a systematic analysis of nanoparticles within the 5-3000 nm range. This capability extends to size distribution, particle counting, and biochemical property assessment, making it a groundbreaking tool for life science and biomedical research.

4 Scatter Channels

• 4 scatter channels: VSSC-1, VSSC-2, FSC, and BSSC.

• Detectable particle range: 5nm-3000nm.

• Exoplorer^TM supports three signal parameters (area, height, and width), effectively distinguishing system background and noise, ensuring accurate optical signal capture.

Sizing Reference Function

A standard algorithm is used for curve fitting to calculate particle size. Sizing results are given in nm and refractive index of the /biological sample is used to determine the size.

Bead-free Absolute Counting

Feature exceptional consistency, stability, and reliability in absolute counting functionality.

Supreme Robust System Stability

• Mean fluorescence intensity variation kept within ±5% for 30 consecutive days

• Operational temperature range:15-28 ℃; flunctuation±2℃

LNP Detection 

LNP Carrying Nucleic Acid Positivity Rate

LNP Sizing and Concentration Data

LNP samples at different dilution factors were acquired, with a calculated original concentratioon RSD of 2%. Experimental results demonstrate the Exoplorer^TM excels in measuring the concentration, particle size and shell rate of LNPs.

Learn More——Precise and Efficient EVs Purity Detection with Exoplorer^TM

Publications Using Exoplorer™ Nano-flow Cytometer

Peer-reviewed publications from researchers using Exoplorer™ Nano-flow Cytometer. Click the DOI to access the original article.

If you would like to obtain the PDF, please contact us.

Chemical Engineering Journal

Publication Date: 1 May 2026

Title: Isolation-to-delivery hydrogel enables efficient isolation and sustained release of exosomes to enhance wound healing

Authors: Lihua Yang, Cenlong Huang, Mingwei Shen, Chenyu Xu, Zonglin Guo, Juan Gallo, Meijin Guo, Ali Mohsin

Read the Article: https://doi.org/10.1016/j.cej.2026.174990.

ACS Nano

Publication Date: March 30, 2026

Title: Noninvasive, Rapid, and Precise Identification of Esophageal Cancer via Salivary Extracellular Vesicle-Based Diagnosis.

Authors: L. Huang, M. Li, W. Liu, D. Lou, Q. Zhu, T. Y. Hu, et al.

Read the Article: https://doi.org/10.1021/acsnano.5c20621

Advanced Science

Publication Date: 19 February 2026

Title: miR-185-5p Derived From hUC-MSC Exosomes via Suspension Culture Under Hypoxic Conditions Promotes Scarless Wound Healing in Mice by Precisely Regulating Collagen I/III Regeneration

Authors: L. Yang, Y. Sun, Q. Yan, et al.

Read the Article: https://doi.org/10.1002/advs.202516120

Journal of Biomedical Optics

Publication Date: 23 Jan 2026

Title: Particle size distribution and concentration of Intralipid® 20%

Authors: Mona Shahsavari, Martine Kuiper, Mendel Engelaer, et al.

Read the Article: https://doi.org/10.1117/1.JBO.31.1.015001

Chinese Pharmaceutical Affairs

Publication Date: 27 June 2025

Title: Measurement of Particle Size of Virus-Like Particle Using Nano-Flow Cytometry

Authors: Lu Qiong, Na Tao, Zhao Chunhui, Zhang Jie, Tang Maoling, Wu Hao, Hu Jinpan, Huang Weijin, Nie Jianhui.

Read the Article: https://doi.org/10.16153/j.1002-7777.2024-11-0052

The Exoplorer^TM Nano-flow Cytometer Handbook Download：https://www.vdobiotech.com/group1/89/c0e64b7084d24dd7be908748b2a22c04.pdf

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